Position Summary TScan is seeking a highly motivated and detail oriented Clinical Scientist with deep expertise in clinical data management and data review to support the execution of our oncology cell therapy clinical programs This unique role sits at the intersection of Clinical Development Clinical Operations Data Management and Biostatistics serving as a critical driver of data quality data integrity and clinical insight generation The Clinical Scientist will be responsible for leading ongoing clinical data review activities developing data review strategies identifying and resolving data issues and ensuring high quality clinical datasets are available to support safety reviews regulatory submissions and clinical decision making The successful candidate will possess a strong scientific background combined with hands on experience in clinical data management EDC systems data visualization tools and cross functional collaboration This position offers an opportunity to play a highly visible role in advancing innovative TCR T therapies through clinical development while helping establish best in class data review and clinical science processes Key Responsibilities Clinical Data Review & Oversight Serve as the clinical lead for ongoing data review activities across TScan clinical studiesDevelop and execute comprehensive data review plans to ensure timely identification and resolution of data discrepancies trends and potential safety signalsReview patient level clinical data to assess completeness consistency protocol compliance and medical relevancePartner with Clinical Operations Data Management Medical Pharmacovigilance and Biostatistics to drive data quality and readinessLead cross functional data review meetings and track resolution of key data issuesClinical Science & Data Interpretation Analyze and interpret emerging clinical safety efficacy and biomarker data to support study conduct and decision makingSupport data cleaning efforts for interim analyses data monitoring committee reviews and regulatory submissionsContribute to clinical narratives safety analyses data listings review and study reportsCollaborate with translational and biomarker teams to integrate clinical and correlative data insightsData Management Collaboration Partner closely with Data Management to review CRFs edit checks data validation plans and data review specificationsProvide clinical input into database design study builds and data collection strategiesSupport UAT testing of EDC systems and associated clinical technologiesReview data transfer specifications and external vendor data integration processesEnsure data review activities align with CDISC standards and regulatory expectationsClinical Development Support Contribute to protocol development endpoint definitions and data collection strategiesParticipate in study team meetings and provide clinical science expertise throughout study executionSupport preparation of clinical study reports CSRs regulatory documents investigator brochures and publicationsAssist with inspection and audit readiness activitiesProcess Improvement & Innovation Develop and implement innovative approaches for ongoing clinical data surveillance and risk based data reviewLeverage data visualization tools and analytics platforms to enhance clinical data review efficiencyContribute to the development of clinical data review SOPs work instructions and best practicesHelp establish scalable processes to support growth of TScans clinical portfolioQualifications Education Advanced degree PharmD PhD MS MPH or equivalent in a life sciences clinical research or related field preferredBachelors degree with significant relevant experience may be consideredExperience 58 years of experience in clinical development clinical science data management or related functions within biotechnology pharmaceutical or CRO environmentsDemonstrated experience performing ongoing clinical data review in oncology or advanced therapy clinical trialsExperience working closely with Data Management and Biostatistics teamsExperience supporting early andor late stage clinical trialsOncology immuno oncology cell therapy CAR T TCR T or hematology experience strongly preferredTechnical Skills Strong understanding of clinical trial conduct GCP ICH guidelines and regulatory requirementsHands on experience with EDC systems eg Medidata Rave Veeva EDC Oracle InformExperience using clinical data review and visualization tools such as Spotfire Tableau JReview SAS or similar platformsFamiliarity with CDISC standards SDTM ADaM and clinical database structuresStrong analytical and problem solving skills with the ability to interpret complex clinical datasetsUnderstanding of external data sources including laboratory imaging biomarker and pharmacokinetic dataLeadership & Collaboration Competencies Strong scientific curiosity and attention to detailAbility to synthesize complex clinical data into actionable insightsExcellent communication and presentation skillsProven ability to work effectively in highly cross functional teamsComfortable operating in a fast paced evolving biotechnology environmentStrong organizational skills with the ability to manage multiple priorities simultaneously About TScan TScan Therapeutics is a fully integrated next generation TCR T cell therapy company Founded in 2018 TScans platform was developed by Stephen Elledge PhD and Tomasz Kula PhD at Brigham and Womens Hospital and Harvard Medical School TScans transformative platform enables rapid discovery of TCRs and targets for engineered T cell therapy This technology is extremely versatile and is applicable across multiple therapeutic areas beyond cancers including autoimmune disorders and infectious diseases Do YOU have the anatomy of a TScanner Our talented compassionate and intelligent team is what makes TScan a Top Place to Work as ranked by The Boston Globe Our state of the art offices with over 70000 square feet of premium lab space including an internal GMP manufacturing suite are an environment that supports innovation camaraderie and professionalism We are passionate fun flexible and team oriented Sound like you Apply today EEO Statement TScan is proud to be an Equal Opportunity Employer All qualified applicants will receive consideration for employment without regard to race color religion age sex national origin disability status genetics protected veteran status citizenship status sexual orientation gender identity or expression or any other characteristic identified by federal state or local laws where we operate TScan provides reasonable accommodations to qualified applicants and employees with disabilities To begin an interactive dialogue with TScan regarding a reasonable accommodation in connection with the hiring process andor to perform the responsibilities of the position for which the applicant has applied please contact the recruiter Pay Range 145000 155000 Pay Transparency TScan Therapeutics pay ranges are established based on external market data from third party compensation surveys and our internal benchmarking This role is eligible for an annual bonus and annual equity awards Some roles may also be eligible for overtime pay in accordance with federal and state requirements Individual compensation within this range is commensurate with a candidates specific qualifications including education overall experience relevant experience and specific skills We strive to ensure that compensation is competitive equitable and aligned with the value each TScanner brings to the role Recruitment & Staffing Agencies TScan Therapeutics does not accept unsolicited resumes from any source other than candidates The submission of unsolicited resumes by recruitment or staffing agencies to TScan Therapeutics or its employees is strictly prohibited unless contacted directly by TScan Therapeutics internal Talent Acquisition team Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of TScan Therapeutics and TScan Therapeutics will not owe any referral or other fees with respect thereto